Eagles at Jaguars
Jacksonville is 3–1 and gets a major stage to prove the first month was not a fluke. Philadelphia is 2–2 and arrives with several offensive stars on the practice report.
PRESSURE: PHILADELPHIATampa Bay already changed the week by handing Dallas a bad home loss. Now San Francisco goes into Seattle at 4–0, Baltimore–Atlanta owns Sunday night, Jacksonville tries to prove 3–1 is real in London, and the injury board could reshape several of the biggest games.
UPDATED • OCTOBER 9, 2026San Francisco is 4–0 and still our No. 1 team. Seattle is 3–1 and the defending champion. This is the exact kind of divisional road game that tells us whether the Niners' first month travels.
Lamar Jackson, Caleb Williams, Saquon Barkley, Ja'Marr Chase, Tee Higgins, Nick Bosa, Mike Evans, Pat Surtain II and several other impact players are on the Week 5 practice board. Final inactive lists still come Sunday.
OPEN THE FULL WEEK 5 INJURY WATCH →Jacksonville is 3–1 and gets a major stage to prove the first month was not a fluke. Philadelphia is 2–2 and arrives with several offensive stars on the practice report.
PRESSURE: PHILADELPHIAVegas is 3–1 after pushing Kansas City to the edge. New England just went into Buffalo and won. This is a real legitimacy game for both.
WATCH: JEANTY • BOWERS • MAYEChicago is 3–1 and has built a physical identity. Green Bay needs the home division win, while Caleb Williams' practice status becomes a major variable.
INJURY WATCH: CALEBCincinnati is trying to stabilize at 2–2. Miami is still searching for its first win. Chase and Higgins are both worth watching through the weekend.
MUST-WIN ENERGYMinnesota is 4–0. New Orleans just gave up five rushing touchdowns. This matchup jumps off the page.
MINNESOTA 4–0Somebody gets the first win. Houston's defense still has talent, but 0–4 is now the season story. Tennessee gets the same desperation.
0–4 VS 0–4Two 2–2 AFC teams fighting to separate from the middle.
AFC SEPARATION GAMECleveland is 3–1 and keeps finding ways to finish. The Jets need offensive stability.
CLEVELAND CAN GET TO 4–1New York is 3–1. Washington has Jayden Daniels back to full practice, but several veteran weapons missed work.
NFC EAST PRESSUREDenver is trying to get above .500. The Chargers are 0–4 and dealing with a long injury list.
L.A. EMERGENCY MODEDetroit needs a response after Carolina. Arizona needs to turn competitive stretches into a full game.
DETROIT RESPONSE GAMEThe game of the week. 4–0 San Francisco goes into Seattle against a 3–1 defending champion with control of the NFC West conversation sitting right there.
4DK GAME OF THE WEEKAtlanta's two-game surge gets the measuring stick we wanted. Lamar Jackson's practice absence is now the biggest variable.
WATCH LAMAR'S STATUSBuffalo has to answer its first loss. The Rams just stole one in Philadelphia.
MONDAY CONTENDER CHECKCarolina Panthers • Kansas City Chiefs