Los Angeles Rams
2021 All Over Again.
14–3
This Rams team feels like 2021 all over again. Reigning MVP Matthew Stafford is coming off 4,707 passing yards, 46 touchdowns and only eight interceptions. Kyren Williams gives them balance, Puka Nacua is already a top-tier receiver, and Davante Adams gives Stafford another reliable veteran target.
Then Los Angeles attacked the defense. Trent McDuffie and Jaylen Watson bring championship experience to a secondary that needed more stability. The Rams then traded Jared Verse plus major draft capital for reigning DPOY Myles Garrett, the single-season sack record holder after 23 sacks in 2025.
And then the ridiculous part: Aaron Donald came out of retirement. Donald joins Garrett, Kobie Turner, Braden Fiske and the rest of a front that can be overwhelming on paper. Health is the only obvious concern with so many veteran stars.
4DK Verdict: The most complete team in the NFC — and my No. 1 seed.
San Francisco 49ers
Health Is Everything.
12–5
San Francisco still has contender-level talent, but injuries have defined too many of their seasons. Brock Purdy, 26, enters the year with a new-old weapon in Deebo Samuel and an old face in a new uniform with Mike Evans.
Christian McCaffrey remains the focal point of everything, George Kittle is still one of the best matchup tight ends in football and rookie De'Zhaun Stribling gives the receiver room another young piece. The biggest offensive concern is still the line, where 38-year-old Trent Williams remains the anchor.
Defensively, the healthy returns matter just as much. Nick Bosa, Fred Warner and returning Dre Greenlaw restore the core personality of the unit, while Osa Odighizuwa gives the interior another proven piece.
4DK Verdict: If healthy, they can beat anybody. No. 5 seed.
Seattle Seahawks
The Champs Lost Pieces, Not Their Identity.
12–5
Seattle has real losses to absorb, but there is still enough here to make another playoff run. Sam Darnold remains the stabilizer at quarterback, and first-round rookie running back Jadarian Price gets an immediate opportunity after Kenneth Walker III left for Kansas City.
Then there is Jaxon Smith-Njigba. After 119 catches, a league-leading 1,793 yards and 10 touchdowns — plus Offensive Player of the Year — JSN has a real argument as the best receiver in football. Rashid Shaheed and Cooper Kupp keep defenses from treating him like the only threat.
Defensively, Mike Macdonald still has Leonard Williams, DeMarcus Lawrence, Byron Murphy II, Ernest Jones IV, Devon Witherspoon, Julian Love and Nick Emmanwori. Losing Coby Bryant, Boye Mafe and Riq Woolen hurts the depth, but the top of the unit remains loaded.
4DK Verdict: Still a playoff team. Still dangerous. No. 7 seed only because this conference is stacked.
Arizona Cardinals
Forget The Record. Watch The Development.
4–13
Arizona is not about contention in 2026. This season is about figuring out which players belong in the next version of the team. Start with Jeremiyah Love, the No. 3 overall pick and the highest-drafted running back since Saquon Barkley.
Jacoby Brissett gives the quarterback room a veteran option, while third-round rookie Carson Beck is the long-term developmental question. Marvin Harrison Jr., Michael Wilson and Trey McBride give whoever plays quarterback legitimate targets.
Defensively, Josh Sweat and Budda Baker are the established veterans, while Walter Nolen III, Will Johnson and Dadrion Taylor-Demerson are among the younger pieces who need to keep developing under first-year head coach Mike LaFleur.
4DK Verdict: 4–13 can still be progress if Love looks special and the young core grows.